Htr2a Polyclonal Antibody for Mouse(Mus musculus) | EIAab.comHtr2a Polyclonal Antibody for Mouse(Mus musculus)

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Htr2a (Gene name),

5-hydroxytryptamine receptor 2A (Protein name ), 5HT2A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Htr2a(Htr2);

Protein name:

5-hydroxytryptamine receptor 2A(5-HT-2;5-HT-2A);

Alternative:

Serotonin receptor 2A;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with MPDZ and INADL. May interact with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2.

Function:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

Subcellular Location:

Cell membrane Multi-pass membrane protein Localizes to the post-synaptic thickening of axo-dendritic synapses.

Protein Attributes:

Sequence length:

471

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

471:

QHSEEMCTDN | IETVNEKVSC | V

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:15558

String:

P35363

Pfam:

PF00001

UniGene:

Mm.214351

SMR:

P35363

STRING:

10090.ENSMUSP00000047774

Uniprot:

P35363

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ELISA Kit for Mouse 5-HT-2

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E10283h

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96T

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ELISA Kit for Mouse 5-HT-2

Cat.:

E10283r

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96T

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ELISA Kit for Mouse 5-HT-2

Cat.:

E10283d

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96T

ELISA Kit for Mouse 5-HT-2

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E10283m

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96T

ELISA Kit for Mouse 5-HT-2

Cat.:

E10283p

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96T

ELISA Kit for Mouse 5-HT-2

Cat.:

E10283b

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96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283p

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96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283r

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96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283b

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MSDS:

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Packing:

96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283d

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96T

CLIA Kit for Mouse 5-HT-2

Cat.:

U10283m

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96T

Polyclonal Antibody for Mouse 5-HT-2

Cat.:

P10283Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse 5-HT-2

Cat.:

P10283Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse 5-HT-2

Cat.:

P10283Rb-h

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40ug/0.2ml

Monoclonal Antibody for Mouse 5-HT-2

Protein for Mouse 5-HT-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Gene structure and expression of the mouse 5-HT2 receptor."
Yang W. , Chen K. , Lan N.C. , Gallaher T.K. , Shih J.C.
J. Neurosci. Res.33:196-204(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice."
Fiorica-Howells E. , Hen R. , Gingrich J. , Li Z. , Gershon M.D.
Am. J. Physiol.282:G877-G893(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
3.

"The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins."
Becamel C. , Gavarini S. , Chanrion B. , Alonso G. , Galeotti N. , Dumuis A. , Bockaert J. , Marin P.
J. Biol. Chem.279:20257-20266(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
4.

"Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice."
Weisstaub N.V. , Zhou M. , Lira A. , Lambe E. , Gonzalez-Maeso J. , Hornung J.P. , Sibille E. , Underwood M. , Itohara S. , Dauer W.T. , Ansorge M.S. , Morelli E. , Mann J.J. , Toth M. , Aghajanian G. , Sealfon S.C. , Hen R. , Gingrich J.A.
Science313:536-540(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;FUNCTION
5.

"Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior."
Gonzalez-Maeso J. , Weisstaub N.V. , Zhou M. , Chan P. , Ivic L. , Ang R. , Lira A. , Bradley-Moore M. , Ge Y. , Zhou Q. , Sealfon S.C. , Gingrich J.A.
Neuron53:439-452(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
6.

"Identification of a serotonin/glutamate receptor complex implicated in psychosis."
Gonzalez-Maeso J. , Ang R.L. , Yuen T. , Chan P. , Weisstaub N.V. , Lopez-Gimenez J.F. , Zhou M. , Okawa Y. , Callado L.F. , Milligan G. , Gingrich J.A. , Filizola M. , Meana J.J. , Sealfon S.C.
Nature452:93-97(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRM2;FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
7.

"Functional crosstalk and heteromerization of serotonin 5-HT2A and dopamine D2 receptors."
Albizu L. , Holloway T. , Gonzalez-Maeso J. , Sealfon S.C.
Neuropharmacology61:770-777(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DRD2;FUNCTION;SUBCELLULAR LOCATION
8.

"5HT(2A) and 5HT(2B) receptors contribute to serotonin-induced vascular dysfunction in diabetes."
Nelson P.M. , Harrod J.S. , Lamping K.G.
Exp. Diabetes Res.2012:398406-398406(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A.mGlu2) receptor heteromerization and its psychoactive behavioral function."
Moreno J.L. , Muguruza C. , Umali A. , Mortillo S. , Holloway T. , Pilar-Cuellar F. , Mocci G. , Seto J. , Callado L.F. , Neve R.L. , Milligan G. , Sealfon S.C. , Lopez-Gimenez J.F. , Meana J.J. , Benson D.L. , Gonzalez-Maeso J.
J. Biol. Chem.287:44301-44319(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION

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